Ultrastructure of decidualization in the pseudopregnant rat.

摘要: Abstract The ultrastructure of the endometrial stroma in rats bearing deciduomata was examined detail on day 9 (day vaginal cornification = 0) pseudopregnancy, together with development from 4 to 8. Five major regions were recognizable 9. 1) In basal zone, which contributes regeneration following decidualization, stromal cells remained fibrocyte-like and separated by wide bands collagen fibrils. Capillaries fenestrated large. 2) capsule surrounding antimesometrial (region the) deciduoma composed flattened cells, showing mitosis, appeared provide a source appositional growth deciduoma. 3) large, tightly packed, polyploid showed morphological evidence protein synthesis activity, an absence smooth endoplasmic reticulum, surface specializations suggestive adhesion (adherens junctions), communication (gap maintenance extensive area (lamellar processes). These came into very close apposition capillary endothelial seldom fenestrated, lacked any continuous lamina, high metabolic activity. 4) loosely packed mesometrial contained structurally supportive, "fixed" population spiny "free" granulated their putative precursors, meshwork sinusoidal capillaries whose endothelium generally supported lamina. 5) peripheral parts glycogenic area, similar deciduoma, many grossly enlarged intercellular spaces undetermined function. at 4, give rise all non-vascular elements except mentioned above, simple fibrocyte-like. Only two distinct regions, subepithelial deep, recognizable. possessed endothelium, complete lamina pericytes. Between days 5 8, divergent forms differentiation according position endometrium. Ultrastructural vasculature also divergence position, leading various types seen Regional variation, levels structural organization, characterize "programmed" decidual response pseudopregnant rat.