Pigment-based micronutrient biosensors
作者： Mark Philip-Walter Styczynski , Daniel M. Watstein , Monica Mcnerney
DOI:
关键词: Pigment 、 Chemistry 、 Zinc 、 Biosensor 、 Micronutrient 、 Vitamin B12 、 Lycopene 、 Violacein 、 Bacteria 、 Food science
摘要: A whole-cell biosensor for a point-of-care assay using genetically engineered bacteria or fungi to report micronutrient, example, zinc levels in blood samples is provided. One embodiment provides micronutrient having gene circuit expressing at least two different pigments response concentrations of the wherein expression pigment visible naked eye and indicative concentration micronutrient. Another third relative pigments. Exemplary micronutrients include but are not limited zinc, iron, vitamin D, B12, iodine, folate. Representative violacein, lycopene, beta-carotene.
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