Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease

作者: C. D. Keene , C. M. P. Rodrigues , T. Eich , M. S. Chhabra , C. J. Steer

DOI: 10.1073/PNAS.162362299

关键词: Genetically modified mousePutamenBile acidTaurochenodeoxycholic acidNeuroprotectionTauroursodeoxycholic acidAnatomyBiologyEndocrinologyHuntington's diseaseHuntingtinInternal medicine

摘要: … Striatal sections (15 μm) were prepared for analysis from vehicle and TUDCA-treated mice. Apoptotic cells were identified by using the ApopTag in situ detection kit (Intergen, Purchase, …

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