Applications of NiFe2O4 nanoparticles for a hyperthermia agent in biomedicine

摘要: Self-heating temperature rising characteristics, cytotoxicity, and magnetic properties of NiFe2O4 nanoparticles have been investigated to confirm the effectiveness as an in vivo hyperthermia agent biomedicine. showed both superparamagnetic ferrimagnetic behaviors depending on particle sizes. The quantitative cytotoxicity test verified that uncoated chitosan-coated had noncytotoxicity. solid state 35nm size first exhibited a maximum self-heating 44.2°C at H0f=5.1×108Am−1s−1. physical nature was primarily thought be due hysteresis loss, Neel rotations, Brownian rotations nanoparticles.