Loading amplification of radiation grafted polymers (crowns and lanterns) and their application in the solid-phase synthesis of hydantoin libraries.

作者: Sylvain Lebreton , Nicholas Newcombe , Mark Bradley

DOI: 10.1023/A:1024867013184

关键词: PolymerOrganic chemistryPolymer chemistryIsocyanateDendrimerSolid-phase synthesisMonomerChemistryHydantoin

摘要: Solid-phase dendrimer chemistry using a symmetrical 1→3C-branched isocyanate monomer was used to prepareradiation-grafted polymers with enhanced loading. Afterevaluation of the physical and chemical properties thesenew high-loading supports, they were tested in multipleparallel synthesis hydantoins.

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