Role of calciotrophic hormones in calcium mobilization of lactation.

摘要: The postpartum period can be a time when profound changes in calcium metabolism and bone mineral density (BMD) occur, particularly association with lactation. We investigated the hypothesis that calciotrophic hormones [1,25-dihydroxyvitamin D, 25-hydroxyvitamin parathyroid hormone (PTH)] are different by lactation practice or status [PTH-related peptide (PTHrP), estradiol, prolactin] have potential role loss recovery associated 1,25-Dihydroxyvitamin PTH, femoral BMD, PTHrP, prolactin, turnover markers were measured at 2 wk 2, 4, 6, 12, 18 mo postparturition 115 women aged 20-40 y (parity: 0-1). Lumbar spine BMD was during period. 1,25-dihydroxyvitamin D concentrations nonlinear across 18-mo Between baseline postparturition, PTH did not decline, while there substantial decline concentrations. differ prolactin status. These classic of lactating women. In summary, patterns change (PTH, D) appeared to independent markers. data do support these three central part mobilization