Life-Threatening Tumor Lysis Syndrome Within 12 Hours of a Single Dose of Corticosteroid in a Patient with Lymphoma

作者: April Brooks , Grady Wick , Damiano Rondelli , José A. L. Arruda , Kalyani Perumal

DOI: 10.1007/S00596-009-0090-5

关键词: Tumor lysis syndromeGastroenterologyLymphomaChemotherapyLaboratory monitoringPathologyLymphoblastic lymphomaCorticosteroidInternal medicineSignificant riskMedicineNephrology

摘要: Tumor lysis syndrome is an oncologic emergency characterized by electrolyte derangements and the frequent development of acute renal failure. We describe a patient with lymphoblastic lymphoma in whom rapid severe tumor developed within 10 h administration single dose corticosteroid. Our case review literature indicate that patients lymphoproliferative malignancies given corticosteroid may be at significant risk for life-threatening syndrome. recommend such receive aggressive laboratory monitoring even setting appropriate prophylaxis.

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