Altered resting state in diabetic neuropathic pain.

作者: Franco Cauda , Katiuscia Sacco , Sergio Duca , Dario Cocito , Federico D'Agata

DOI: 10.1371/JOURNAL.PONE.0004542

关键词: Resting state fMRIAnesthesiaFunctional magnetic resonance imagingDiabetes mellitusNeuroimagingBiologyNeuralgiaCingulate cortexBrain mappingNeuropathic pain

摘要: Background The spontaneous component of neuropathic pain (NP) has not been explored sufficiently with neuroimaging techniques, given the difficulty to coax out brain components that sustain background ongoing pain. Here, we address for first time correlates this in an fMRI study a group eight patients suffering from diabetic and healthy control subjects. Specifically, studied functional connectivity is associated spatial independent analysis (sICA).

参考文章(52)
Vincenzo Bonicalzi, Sergio Canavero, Central Pain Syndrome: Pathophysiology, Diagnosis and Management ,(2007)
George Paxinos, Jürgen K. Mai, The human nervous system Elsevier Academic Press. ,(2004)
Erkki Oja, Aapo Hyvarinen, Juha Karhunen, Independent Component Analysis ,(2001)
Eugene M. Izhikevich, Dynamical Systems in Neuroscience ,(2006)
M. Manuguerra, G. C. Caramenti, M. L. Sotgiu, M. Brambilla, G. E. M. Biella, M. Valente, Chronic pain as expression of neural substrates. Issues from the neuronal dynamics and mutual relations. Archives Italiennes De Biologie. ,vol. 142, pp. 275- 283 ,(2004) , 10.4449/AIB.V142I3.376
M. D. Fox, A. Z. Snyder, J. L. Vincent, M. Corbetta, D. C. Van Essen, M. E. Raichle, The human brain is intrinsically organized into dynamic, anticorrelated functional networks Proceedings of the National Academy of Sciences of the United States of America. ,vol. 102, pp. 9673- 9678 ,(2005) , 10.1073/PNAS.0504136102
Michael Petrides, Deepak N. Pandya, The Frontal Cortex The Human Nervous System. pp. 988- 1011 ,(2012) , 10.1016/B978-0-12-374236-0.10026-4
Michael S Gazzaniga, James M Sprague, None, The Cognitive Neurosciences ,(1995)
Emeran A. Mayer, Steven Berman, Brandall Suyenobu, Jennifer Labus, Mark A. Mandelkern, Bruce D. Naliboff, Lin Chang, Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis Pain. ,vol. 115, pp. 398- 409 ,(2005) , 10.1016/J.PAIN.2005.03.023
Michael D. Fox, Marcus E. Raichle, Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nature Reviews Neuroscience. ,vol. 8, pp. 700- 711 ,(2007) , 10.1038/NRN2201