Molecular Insight into the Discrepancy of Antitubercular Activity between 8-Nitro and 8-Cyano Benzothiazinones
作者： Gang Zhang , Daoxing Chen , Sufang Wang , Hualong Chen , Ning Wei
关键词: Stereochemistry 、 Nitro 、 Molecular dynamics 、 Chemistry
摘要: Benzothiazinones with 8‐NO2 group is a novel class of compounds with potent antitubercular activity, especially BTZ043 and PBTZ169, which covalently inhibit DprE1. 8 …
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