Formation and characterization of ordered bicontinuous microemulsions.
作者： Anna Kogan , Deborah E. Shalev , Uri Raviv , Abraham Aserin , Nissim Garti
DOI: 10.1021/JP901617G
关键词: Dynamic light scattering 、 Crystallography 、 Lamellar phase 、 Small-angle X-ray scattering 、 Lamellar structure 、 Mesophase 、 Materials science 、 Phase (matter) 、 Lyotropic liquid crystal 、 Microemulsion
摘要: Ordered bicontinuous microstructures formed in a fully water-dilutable, pseudoternary unique nonionic microemulsion were obtained and characterized. The concentrate contained mixture of triacetin/d-alpha-tocopherol acetate/ethanol/Tween 60. Upon dilution, the was transformed from reversed micellar system to oil-in-water droplets. transformation occurred through an intermediate phase ordered structures. factors that governed construction this phase, its physical structural properties, characterized detail. techniques used included small angle X-ray scattering (SAXS), self-diffusion quantum filtered NMR, differential scanning calorimetry, rheology measurements, electrical conductivity, dynamic light scattering. This mesophase displays properties along with some characteristics lyotropic liquid crystals (but is not two). Similar microemulsions, structures transparent spontaneously exhibited thermodynamic stability. Yet, unlike they showed short-range order at room temperature. Additionally, non-Newtonian flow behavior, characteristic lamellar microemulsions upon heating (to 25 degrees C) existing low temperatures (5 C). main feature governing formation amphiphilic nature oil blends composed d-alpha-tocopherol acetate triacetin. oils functioned as cosurfactants, altering packing parameter surfactant leading order. These might have drug or nutraceutical delivery advantages.
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