Preanalytical phase in haematology

摘要: The preanalytical phase is particularly important in hematology, where counts of particles and cells are performed whole anticoagulated blood. correct use concentration anticoagulant mandatory to avoid spurious results, which can influence clinical decision. EDTA the choice, but it has some limits, especially for preserving stability shape platelets. Stability haematological parameters high, with exception leukocytes reticulocytes. However, (and instrumental precision) should be evaluated together biological variability individuality index various parameters. Hematological tests also influenced interfered by high amounts lipids chylomicrons. mixing procedure tubes after blood drawing before analysis crucial obtaining valid data. There examples interferences on automated analyzers used diagnosing screening pathological conditions. Cryoglobulins erythrocytes parasites induce results WBC, RBC PLT, repeatability these could alerting pathologist reveal presence proteins or parasites. New have been proposed modern analyzers, directly defined calculated from traditional measures, impact new often dependent variables.