LACK OF DISTANT MIGRATION AFTER INJECTION OF A sup 125 IODINE LABELED DEXTRANOMER BASED IMPLANT INTO THE RABBIT BLADDER

作者: A.M. Stenberg , A. Sundin , B.S. Larsson , G. Lackgren , A. Stenberg

DOI: 10.1016/S0022-5347(01)64185-5

关键词: ScintigraphyIodineThyroidIodine RadioisotopesUrologyPathologyUrinary bladderDextranomerMedicineImplantVesicoureteral reflux

摘要: AbstractPurpose: In recent years endoscopic treatment of stress incontinence and vesicoureteral reflux has been introduced. Reports possible particle migration the injected material to distant organs in humans experimental animals have led a search for biological nonmigration products. An implant found good clinical effect these conditions is dextranomer hyaluronan. We performed this study rabbits investigate particles.Materials Methods: 125 Iodine labeled particles were into submucosal space rabbit bladders, samples blood various tissues examined radioactivity at scheduled intervals during 28-day period. Furthermore, whole body autoradiography was 1 day, 4 weeks after injection.Results: Radioactivity all but it remained background activity level except thyroid, where uptake representing free125 iodine was...

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