Endoscopic Treatment of Premalignant and Early Esophageal Malignancy

摘要: Barrett’s esophagus (BE) is a well-known risk factor for esophageal adenocarcinoma, and progression of metaplasia through dysplasia to adenocarcinoma widely accepted theory carcinogenesis. High-grade (HGD) has high cancer, resection (esophagectomy) been recommended as standard surgical therapy treat HGD based on the previous studies demonstrating that incidence concomitant invasive cancer in surgically resected specimens patients with biopsy-proven reported be approximately 40 %. Esophagectomy one most surgeries upper gastrointestinal tract associated mortality morbidity even recent refinement techniques perioperative care. Given lymph node involvement T1a unlikely (<2 %), esophagectomy may unreasonably invasive. However, have chance cure disease, although overall prognosis poor 5-year survival 15 % despite multidisciplinary approaches including chemoradiation therapy. Therefore, it extremely important determine what best approach this population accomplish without residual or recurrent while minimizing postoperative mortality.