Corticosteroids in Pediatric Endocrinology
作者： Cosimo Giannini , Angelika Mohn
DOI: 10.1007/978-3-319-16056-6_11
关键词: Internal medicine 、 Endocrinology 、 Adrenal insufficiency 、 Adrenal cortex 、 Pediatric endocrinology 、 Hormone 、 Therapeutic approach 、 Glucocorticoid 、 Medicine 、 Congenital adrenal hyperplasia 、 Cushing Disease
摘要: Glucocorticoids are human steroid hormones secreted by the adrenal cortex that play a critical role in several biologic processes. At “pharmacologic” or “stress-related” doses, glucocorticoids irreplaceable therapeutic means for many allergic, inflammatory, autoimmune, and lymphoproliferative diseases. also remain cornerstone of treatment certain life-threatening endocrinopathies childhood, such as congenital hyperplasia, Addison disease, replacement therapy subjects with secondary hypothalamic–pituitary–adrenal axis deficit. In this chapter physiology is described. addition, approach to glucocorticoid most relevant childhood (i.e., Cushing disease) elucidated.
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