Elective neck dissection for carcinomas of the oral cavity: occult metastases, neck recurrences, and adjuvant treatment of pathologically positive necks

作者: Peter Zbären , Michel Nuyens , Marco Caversaccio , Edouard Stauffer

DOI: 10.1016/J.AMJSURG.2006.01.052

关键词: OccultDissectionCarcinomaMetastasisMedicineNeck dissectionOral Cavity CarcinomaRadiation therapySurgeryCancerGeneral Medicine

摘要: Abstract Background Supraomohyoid neck dissection (SOHND) is currently performed in patients with carcinoma of the oral cavity clinically negative neck. Most investigators consider SOHND as a staging procedure. Methods Records 100 cancer and undergoing were reviewed. The rate significance occult metastases are evaluated, recurrences analyzed indication adjuvant radiation pN+ necks discussed. Results In 34 1814 lymph nodes, metastatic disease was detected follows: 30 macrometastases 4 micrometastases. 13 (38%), extracapsular spread observed. Twenty (20%) had to be upstaged. 9 87 (10%) without local recurrence minimal follow-up 24 months, 5 ipsilateral (4 within field) contralateral Regional developed 4% 35% pN0 necks, respectively. Conclusions 20% tumors neck, disclosed. Neck significantly more often than those necks. To evaluate exact for an treatment cN0/pN+ prospective studies should performed.

参考文章(48)
Hiroyuki Hamakawa, Masakuni Fukizumi, Yang Bao, Tomoki Sumida, Akiko Onishi, Hiroaki Tanioka, Hidemitsu Sato, Eiji Yumoto, Genetic diagnosis of micrometastasis based on SCC antigen mRNA in cervical lymph nodes of head and neck cancer. Clinical & Experimental Metastasis. ,vol. 17, pp. 593- 599 ,(1999) , 10.1023/A:1006732911057
TNM classification of malignant tumours Published in <b>2010</b> in Chichester, West Sussex, UK ;Hoboken, NJ by Wiley-Blackwell. ,(1987) , 10.1007/978-3-642-82982-6
Sheng-Po Hao, Ngan-Ming Tsang, The role of supraomohyoid neck dissection in patients of oral cavity carcinoma. Oral Oncology. ,vol. 38, pp. 309- 312 ,(2002) , 10.1016/S1368-8375(01)00061-6
Debra M. Don, Thomas C. Calcaterra, Yoshimi Anzai, Robert B. Lufkin, Yao-Shi Fu, Evaluation of cervical lymph node metastases in squamous cell carcinoma of the head and neck. Laryngoscope. ,vol. 105, pp. 669- 674 ,(1995) , 10.1288/00005537-199507000-00001
Francisco J Civantos, Carmen Gomez, Carlos Duque, Felipe Pedroso, William Jarrard Goodwin, Donald T Weed, David Arnold, Fred Moffat, None, Sentinel node biopsy in oral cavity cancer: correlation with PET scan and immunohistochemistry. Head and Neck-journal for The Sciences and Specialties of The Head and Neck. ,vol. 25, pp. 1- 9 ,(2003) , 10.1002/HED.10213
P. Ambrosch, L. Freudenberg, M. Kron, W. Steiner, Selective neck dissection in the management of squamous cell carcinoma of the upper digestive tract European Archives of Oto-rhino-laryngology. ,vol. 253, pp. 329- 335 ,(1996) , 10.1007/BF00178287
Laurent Tschopp, Michel Nuyens, Edouard Stauffer, Thomas Krause, Peter Zbären, The value of frozen section analysis of the sentinel lymph node in clinically N0 squamous cell carcinoma of the oral cavity and oropharynx. Otolaryngology-Head and Neck Surgery. ,vol. 132, pp. 99- 102 ,(2005) , 10.1016/J.OTOHNS.2004.09.010
A. Sefik Hosal, Ricardo L. Carrau, Jonas T. Johnson, Eugene N. Myers, Selective Neck Dissection in the Management of the Clinically Node‐Negative Neck Laryngoscope. ,vol. 110, pp. 2037- 2040 ,(2000) , 10.1097/00005537-200012000-00011
André L Carvalho, Luiz P Kowalski, José Alexandre Leal Borges, Samuel Aguiar, José Magrin, None, Ipsilateral neck cancer recurrences after elective supraomohyoid neck dissection. Archives of Otolaryngology-head & Neck Surgery. ,vol. 126, pp. 410- 412 ,(2000) , 10.1001/ARCHOTOL.126.3.410