Lipoic acid analogs useful as provitamins and antioxidants

摘要: This invention comprises administering to a human or animal in need of treatment an effective amount antioxidant lipoic acid derivative and/or pharmaceutically acceptable salts, solvates stereoisomers thereof for the prevention pathological inflammatory, proliferative, degenerative, metabolic neovascular diseases, virus prion-related diseases. Another aspect is use compounds this ameliorating improving nutritional cosmetic conditions related aging as result oxidative stress, environmental hereditary conditions, such skin (wrinkles and sagging skin) other organ systems, damage from disease (e.g. erectile dysfunction) toxins. Methods synthesizing novel derivatives their preventing treating diseases caused by stress free radical mediated are described. The compositions used protect ultraviolet radiation desiccation, provide improved feel desquamating, cleansing clarifying skin. For these incorporated into sunscreen products, soap, moisturizing lotions, toners, care products. described increase cellular viability, promote cytoprotection, decrease production inflammatory mediators cells tissues, may be administered subcutaneously, topically, orally, mucosally, intravenously, intramuscularly.