Processes for delivery of viscous drug therapies
作者： Amy M. Heintz , Steven M. Risser , John D. Clay , Jeffrey L. Ellis , Eric C. Scribben
DOI:
关键词: Core (manufacturing) 、 Viscous liquid 、 Viscosity 、 Biomedical engineering 、 Materials science 、 Annular flow 、 A protein
摘要: Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as protein therapeutic formulation. The high-viscosity surrounded by low-viscosity fluid, and lubricates passage fluid. This allows use formulations that have higher concentration viscosity at comparatively reduced injection forces times. Several different embodiments devices provide core are described herein.
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