The development of high hydrostatic pressure processes as an alternative to other pathogen reduction methods.

作者: G. Demazeau , N. Rivalain

DOI: 10.1111/J.1365-2672.2011.05000.X

关键词: Hydrostatic pressureBiochemical engineeringLow energyBiological mediaPathogen reductionPressure sensitiveLiquid phaseHigh pressure

摘要: In biology, scientist's interest for high hydrostatic pressure (HHP) has increased over the last 20 years, both research and industrial developments, mainly because of low energy associated with its application in liquid phase capacity to inactivate pathogens. It is now considered as an interesting alternative heat treatments inactivation contaminants many products, from foods pharmaceutical preparations. This statement implies different objectives according type product. The therapeutic properties preparations or other biological media physiological importance are general specific well-defined molecules such proteins. Their activity depends on their spatial conformation, maintained by weak chemical bonds that often sensitive. this case, optimization a HHP process can be more complex than foods, which organoleptic less sensitive, evaluation preservation subjective highly dependant consumers acceptance. objective review therefore underline how, even if basic concept pathogen reduction using same whatever product, major differences arise product itself final use.

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