作者: George U Eleje , Joseph I Adinma , Samuel Ghasi , Joseph I Ikechebelu , Anthony O Igwegbe
DOI: 10.1016/J.IJGO.2014.04.016
关键词: Premature rupture of membranes 、 Metronidazole 、 Cefuroxime 、 Medicine 、 Pregnancy 、 Cefixime 、 Surgery 、 Antibiotic sensitivity 、 Erythromycin 、 Internal medicine 、 Antibiotics
摘要: Abstract Objective To identify microbes prevalent in the genital tract of pregnant women with preterm premature rupture membranes (PPROM) and to assess susceptibility microbial isolates a range antibiotics determine appropriate for treating cases PPROM resource-limited settings. Methods A prospective cross-sectional study was undertaken involving (n = 105) without confirmed diagnosis admitted Nnamdi Azikiwe University Teaching Hospital, southeast Nigeria, between January 1, 2011, April 30, 2013. Endocervical swabs were collected from all participants examined microbiologically. Antibiotic sensitivity testing performed using Kirby–Bauer disk diffusion. Results Streptococcus spp., Staphylococcus aureus , Escherichia coli significantly more among than those ( P Conclusion For first 48 hours, should receive an intravenous dose combining ampicillin-sulbactam, cefixime, cefuroxime, or erythromycin metronidazole followed by oral administration chosen antibiotic combination complete 7-day course.