Right ventricular dynamics during left ventricular assistance in closed-chest dogs
作者： Marc R. Moon , Luis J. Castro , Abe DeAnda , Yasuko Tomizawa , George T. Daughters
DOI: 10.1016/0003-4975(93)90402-4
关键词: Preload 、 Heart disease 、 Afterload 、 Cardiology 、 Ventricular assist device 、 Anesthesia 、 Contractility 、 Occlusion 、 Ventricle 、 Internal medicine 、 Medicine 、 Hemodynamics
摘要: Abstract To determine the effects of left ventricular assist device (LVAD) support on global right (RV) systolic mechanics, 8 closed-chest, conscious, sedated dogs were studied after placement an LVAD (left ventricle to femoral artery bypass) and implantation 27 tantalum markers into RV walls for computation biventricular volumes geometry. Biplane cinefluoroscopic marker images hemodynamic parameters recorded during transient vena caval occlusion at various levels support. Right contractility was assessed using end-systolic elastance preload recruitable stroke work, myocardial (pump) efficiency converting mechanical energy external work (stroke work/total pressure-volume area) calculated. With full support, end-diastolic volume increased from 60 ± 15 62 17 mL ( p 5 leftward septal shift > 0.74 0.33, respectively). Therefore, is impaired with shifting, but myocardiol power output are maintained through a decrease in afterload increase preload.
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