Sirolimus does not exhibit nephrotoxicity compared to cyclosporine in renal transplant recipients.

作者: José M. Morales , Lars Wramner , Henri Kreis , Dominique Durand , Josep M. Campistol

DOI: 10.1034/J.1600-6143.2002.20507.X

关键词: UrologyRenal functionKidney transplantationTransplantationSirolimusMycophenolateAzathioprineClinical trialNephrotoxicityMedicine

摘要: Sirolimus and cyclosporine (CsA) prevent acute rejection in man when used as primary therapies in triple drug regimens. Sirolimus does not act via the calcineurin pathway and …

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