Vitamin D and Bone Mineral Metabolism in Hepatogastrointestinal Diseases

摘要: Publisher Summary The mineral constituents of bone come from the diet and must be absorbed ingested food in intestine. Vitamin D, through its active metabolite 1,25-dihydroxyvitamin D (1,25(OH)2D), regulates intestinal absorption two major bone, calcium, phosphate. Although synthesized skin under influence ultraviolet light, vitamin is also an important dietary constituent especially circumstances reduced exposure to light. Therefore, dependent on adequate supply phosphate, diet, abnormalities hepatogastrointestinal tract, which impair their further metabolism, cause disease. disease resulting calcium malabsorption complicates processes tract. Many these disorders result both osteoporosis osteomalacia. Furthermore, gastrointestinal diseases lead disease, primarily although presence may itself intake or limited sunlight. Last but not least, chronic inflammation as inflammatory bowel contribute increased resorption a potentially vitamin-D-regulated fashion.