Pimecrolimus 1% cream for the treatment of rosacea
作者： Moon-Bum KIM , Gun-Wook KIM , Hyun-Je PARK , Hoon-Soo KIM , Hyun-Woo CHIN
DOI: 10.1111/J.1346-8138.2011.01223.X
关键词: Pimecrolimus 、 Treatment options 、 Calcineurin 、 Pimecrolimus 1% cream 、 Clinical trial 、 Rosacea 、 Dermatology 、 Erythema 、 Clinical efficacy 、 Medicine
摘要: Rosacea is a common inflammatory skin disorder; the pathogenesis unclear. Various treatment options for rosacea are available, but most have limited effectiveness. The aim of this study was to investigate efficacy and safety 1% pimecrolimus cream rosacea. Thirty patients with were enrolled in 4-week, single-center, open-label cream. Patients instructed apply their faces twice daily not permitted use any other agents. Clinical evaluated by grading system using photographic documentation mexameter. 26 who completed experienced significantly reduced clinical scores from 9.65 ± 1.79 at baseline 7.27 2.11 end (P < 0.05). mexameter-measured erythema index decreased 418.54 89.56 382.23 80.04 week 4 side-effects mostly transient local irritations. results suggest that an effective well-tolerated mild moderate
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