Redox-Related Mechanisms to Rebalance Cancer-Deregulated Cell Growth

摘要: A delicate balance exists between the process of carcinogenesis and tissue regeneration. A number malignant tumours are considered outcome an impaired or incomplete regeneration process, resulting in persistently dividing cells. Regeneration-competent tissues animals able to prevent counteract growth abnormalities seem to have a low vulnerability chemical carcinogenesis. Cancer cell survival depends, among other things, on various redox-related mechanisms, which are targets currently developed therapies. Disadvantages these therapies lack specificity and drug resistance. As majority mechanisms also play important role in successful coordinated functioning reproduction, regeneration offers unique parallel context for modern cancer research. This review focuses interconnections regeneration and how understanding regenerative forces redox-controlled mechanisms could contribute identification new therapeutic block and survival