Guluronate oligosaccharides as enhancers of nanoparticle drug delivery in the oral cavity
作者： Catherine Taylor Nordgård , Astrid Bjørkøy , Kurt I. Draget
DOI: 10.1016/J.BCDF.2014.12.004
关键词: Enhancer 、 Nanotechnology 、 Penetration (firestop) 、 Drug delivery 、 Nanomedicine 、 Saliva 、 Nanoparticle 、 Oral cavity 、 Mucus 、 Chemistry
摘要: Abstract Guluronate oligomers have been shown to modify the gastrointestinal mucus barrier and improve nanoparticle penetration. Here we investigate effect of guluronate on mobility in saliva, a central extracellular oral cavity. reduced aggregation saliva improved over above that which would be expected result from decrease size. As such may interest for nanomedicine delivery
elsevier.com
sci-hub.se 参考文章(40)
Bertrand D.E. RAYNAL, Timothy E. HARDINGHAM, David J. THORNTON, John K. SHEEHAN, Concentrated solutions of salivary MUC5B mucin do not replicate the gel-forming properties of saliva Biochemical Journal. ,vol. 362, pp. 289- 296 ,(2002) , 10.1042/0264-6021:3620289
Alexander T Florence, Nasir Hussain, Transcytosis of nanoparticle and dendrimer delivery systems: evolving vistas Advanced Drug Delivery Reviews. ,vol. 50, pp. S69- S89 ,(2001) , 10.1016/S0169-409X(01)00184-3
Monique H. Vingerhoeds, Theo B.J. Blijdenstein, Franklin D. Zoet, George A. van Aken, Emulsion flocculation induced by saliva and mucin Food Hydrocolloids. ,vol. 19, pp. 915- 922 ,(2005) , 10.1016/J.FOODHYD.2004.12.005
Marit Sletmoen, Gjertrud Maurstad, Catherine Taylor Nordgård, Kurt Ingar Draget, Bjørn Torger Stokke, Oligoguluronate induced competitive displacement of mucin–alginate interactions: relevance for mucolytic function Soft Matter. ,vol. 8, pp. 8413- 8421 ,(2012) , 10.1039/C2SM26256H
Rajesh Singh, James W. Lillard, Nanoparticle-based targeted drug delivery Experimental and Molecular Pathology. ,vol. 86, pp. 215- 223 ,(2009) , 10.1016/J.YEXMP.2008.12.004
Jieying Jing, Yu Zhang, Jiangyu Liang, Qingbo Zhang, Erika Bryant, Carolina Avendano, Vicki L. Colvin, Yiding Wang, Wenying Li, William W. Yu, One-step reverse precipitation synthesis of water-dispersible superparamagnetic magnetite nanoparticles Journal of Nanoparticle Research. ,vol. 14, pp. 1- 8 ,(2012) , 10.1007/S11051-012-0827-3
Bertrand D. E. Raynal, Timothy E. Hardingham, John K. Sheehan, David J. Thornton, Calcium-dependent protein interactions in MUC5B provide reversible cross-links in salivary mucus. Journal of Biological Chemistry. ,vol. 278, pp. 28703- 28710 ,(2003) , 10.1074/JBC.M304632200
P.-O. GLANTZ, S. E. FRIBERG, C. E. CHRISTERSSON, R. E. BAIER, Surface and colloid chemical aspects of saliva particle interactions Journal of Oral Rehabilitation. ,vol. 22, pp. 585- 588 ,(1995) , 10.1111/J.1365-2842.1995.TB01053.X
Cindy Gunawan, May Lim, Christopher P. Marquis, Rose Amal, Nanoparticle-protein corona complexes govern the biological fates and functions of nanoparticles. Journal of Materials Chemistry B. ,vol. 2, pp. 2060- 2083 ,(2014) , 10.1039/C3TB21526A
Hans Grasdalen, High-field, 1H-n.m.r. spectroscopy of alginate: sequential structure and linkage conformations Carbohydrate Research. ,vol. 118, pp. 255- 260 ,(1983) , 10.1016/0008-6215(83)88053-7