Has the amyloid cascade hypothesis for Alzheimer's disease been proved?

作者: John Hardy

DOI: 10.2174/156720506775697098

关键词: Amyloid precursor proteinFunction (biology)DiseaseAmyloidPeptideNeuroscienceBiologyPathogenesisNeurotoxicityTransgene

摘要: … amyloid cascade hypothesis and point out their limitations … amyloid cascade hypothesis has been the dominant organizing principle behind Alzheimer’s research [1-3]. This hypothesis …

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