Travel‐Associated Dengue Infections in the United States, 1996 to 2005

摘要: Background. As the incidence of dengue increases globally, US travelers to endemic areas may be at an increased risk travel-associated dengue. Methods. Data from Centers for Disease Control and Prevention's laboratory-based Passive Dengue Surveillance System (PDSS) were used describe trends in reported January 1, 1996 December 31, 2005. The PDSS relies on provider-initiated requests diagnostic testing serum samples via state health departments. A case was defined as a laboratory-positive infection resident 50 states District Columbia who had been dengue-endemic area within 14 days before symptom onset. confirmed by serologic virologic techniques. Results. One thousand one hundred ninety-six suspected cases reported—334 (28%) laboratory-positive, 597 (50%) laboratory-negative, 265 (22%) laboratory-indeterminate. varied 2005, but overall increase with no significant trend (53.5 121.3 per 108 travelers, p = 0.36). most commonly visited regions Caribbean, Mexico Central America, Asia. median age 37 years (range: <1 75 y) 166 male. Of 334 cases, 41 (12%) hospitalized, 2 (1%) died. Conclusions. Residents traveling are need instructed appropriate prevention measures prior travel. Especially light potential transmissibility virus blood transfusion, consistent reporting infections is essential.