Palmitoylation in Alzheimers disease and other neurodegenerative diseases
作者： Eunsil Cho , Mikyoung Park
DOI: 10.1016/J.PHRS.2016.06.008
关键词: Long-term potentiation 、 ABCA1 、 Palmitoylation 、 Neuroscience 、 NDEL1 、 Disease 、 Alzheimer's disease 、 PICK1 、 Acyltransferases 、 Chemistry
摘要: … intracellular organelles such as the endoplasmic reticulum (ER), … PPT1 itself, like APT1 and APT2, is also palmitoylated at C6 … Unlike APT1 but similar to PPT2, APTL1 features a narrow …
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sci-hub.se 参考文章(280)
E. Hellsten, J. Vesa, V. M. Olkkonen, A. Jalanko, L. Peltonen, Human palmitoyl protein thioesterase: evidence for lysosomal targeting of the enzyme and disturbed cellular routing in infantile neuronal ceroid lipofuscinosis. The EMBO Journal. ,vol. 15, pp. 5240- 5245 ,(1996) , 10.1002/J.1460-2075.1996.TB00909.X
M Koegl, P Zlatkine, S C Ley, S A Courtneidge, A I Magee, Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif Biochemical Journal. ,vol. 303, pp. 749- 753 ,(1994) , 10.1042/BJ3030749
Daniel J Whitcomb, Ellen L Hogg, Philip Regan, Thomas Piers, Priyanka Narayan, Garry Whitehead, Bryony L Winters, Dong-Hyun Kim, Eunjoon Kim, Peter St George-Hyslop, David Klenerman, Graham L Collingridge, Jihoon Jo, Kwangwook Cho, None, Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus Scientific Reports. ,vol. 5, pp. 10934- 10934 ,(2015) , 10.1038/SREP10934
Valeska Berg, Marion Rusch, Nachiket Vartak, Christian Jüngst, Astrid Schauss, Herbert Waldmann, Christian Hedberg, Christian P. Pallasch, Philippe I. H. Bastiaens, Michael Hallek, Clemens-Martin Wendtner, Lukas P. Frenzel, miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL Blood. ,vol. 125, pp. 2948- 2957 ,(2014) , 10.1182/BLOOD-2014-07-586511
K. Iqbal, I. Grundke-Iqbal, Alzheimer neurofibrillary degeneration: significance, etiopathogenesis, therapeutics and prevention. Journal of Cellular and Molecular Medicine. ,vol. 12, pp. 38- 55 ,(2007) , 10.1111/J.1582-4934.2008.00225.X
Steven J. Afendis, Linda A. Verkruyse, Clive A. Slaughter, Laura A. Camp, Sandra L. Hofmann, Molecular cloning and expression of palmitoyl-protein thioesterase. Journal of Biological Chemistry. ,vol. 269, pp. 23212- 23219 ,(1994) , 10.1016/S0021-9258(17)31641-1
Kazumi Motoki, Hideaki Kume, Akiko Oda, Akira Tamaoka, Ai Hosaka, Fuyuki Kametani, Wataru Araki, Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutant. Brain and behavior. ,vol. 2, pp. 270- 282 ,(2012) , 10.1002/BRB3.52
L.A. Camp, S.L. Hofmann, Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras. Journal of Biological Chemistry. ,vol. 268, pp. 22566- 22574 ,(1993) , 10.1016/S0021-9258(18)41567-0
Takashi Toyoda, Hiroyuki Sugimoto, Satoshi Yamashita, Sequence, expression in Escherichia coli, and characterization of lysophospholipase II. Biochimica et Biophysica Acta. ,vol. 1437, pp. 182- 193 ,(1999) , 10.1016/S1388-1981(99)00007-4
Thomas Faul, Micha Gawlik, Martin Bauer, Sven Jung, Bruno Pfuhlmann, Burkhard Jabs, Michael Knapp, Gerald Stöber, ZDHHC8 as a candidate gene for schizophrenia: Analysis of a putative functional intronic marker in case-control and family-based association studies BMC Psychiatry. ,vol. 5, pp. 35- 35 ,(2005) , 10.1186/1471-244X-5-35