Assisted Reproductive Technology and Congenital Malformations

摘要: Assisted reproductive technology (ART) encompasses all medical intervention used to assist people becoming parents, mainly but not solely as a result of infertility. In vitro fertilisation (IVF) is the cornerstone ART. It involves stimulating ovaries, retrieving and culturing oocytes which are then inseminated with capacitated spermatozoa. The embryo cultured transferred into uterus. first successful IVF pregnancy came term in 1978. Since numbers have rapidly increased it now accounts for nearly 2% births UK more than 4 million worldwide (Human Fertilisation Embryology Authority, 2011; ICMART, 2008).