The prevalence of congenital anomalies in Europe.

摘要: EUROCAT (European Surveillance of Congenital Anomalies) is the network population-based registers congenital anomaly in Europe, with a common protocol and data quality review, covering 1.5 million annual births 22 countries. recorded total prevalence major anomalies 23.9 per 1,000 for 2003-2007. 80% were livebirths. 2.5% livebirths died first week life. 2.0% stillbirths or fetal deaths from 20 weeks gestation. 17.6% all cases terminations pregnancy following prenatal diagnosis (TOPFA). Thus, overwhelmingly concern children surviving early neonatal period, who have important medical, social educational needs. The chromosomal was 3.6 births, contributing 28% stillbirths/fetal gestation anomaly, 48% TOPFA. heart defects (CHD) most non-chromosomal subgroup, at 6.5 followed by limb (3.8 1,000), urinary system (3.1 1,000) nervous (2.3 1,000). In 2004, perinatal mortality associated 0.93 TOPFA 4.4 considerable country variation. Primary prevention population based on controlling environmental risk factors crucial policy priority, including preconceptional care whole approaches.