Monitoring of Serum Total Cortisol Level in Burned Traumatic Patients

摘要: Background: Systematic inflammatory syndrome causes death in many conditions. Inflammation and anti-inflammation parameters variation monitoring were done by different clinical lab methods, however, determining the progression of inflammation is very important for on time interference, gaining best results, cost controlling. In this condition, adrenal insufficiency’s water electrolyte disorders, circulatory failure, uncontrolled response, which important. Routine serum total cortisol level SIRS not advised as yet, corticosteroid was used blindly according to hemodynamic condition physician diagnosis. Objectives: pilot study, ability first three days burned ICU traumatic patients studied outcoming improvement. Methods: A 60 patients, 15 - 70 years old, < 80% burn, with systemic response syndrome, during admission ICU, that weren’t included exclusion criteria (patients history insufficiency or corton usage, recent drug etomidate ketoconazole), divided randomly between two groups 30 patients. The group considered under routine treatment second group, besides methods daily measurement at 8 o’clock, find ug/dL, replacement therapy 50 mg hydrocortisone IV, four times a day. Results: None had drop their days. Among more than normal, 20% (6 patients) died. Conclusions: Despite fact may happen, it prevalent, wise consider an effective parameter measures.