作者: Ruth McCaffrey , Daniel St Johnston , Acaimo González-Reyes
DOI: 10.1002/DVDY.20620
关键词: Mutant 、 Oocyte 、 Cell biology 、 Karyosome formation 、 Somatic cell 、 Biology 、 Germline 、 Meiosis 、 Genetics 、 Oogenesis 、 Phenotype
摘要: The establishment of polarity in Drosophila requires the correct specification oocyte early stages oogenesis, its positioning at posterior egg chamber, and signalling events between adjacent follicle cells. As a consequence, anterior-posterior dorsal-ventral axes are fixed. localisation depends on cadherin-mediated adhesion Here we show that dicephalic mutants affect without interfering with germarium. Unlike other also placement oocyte, neither gurken expression nor karyosome formation during meiosis. By analysing detail mutant phenotypes dicephalic, find cyst germaria is defective it shares some similarities cysts lack DE-cadherin germline We propose model which involved proper somatic