Acute renal failure and the MELAS syndrome, a mitochondrial encephalomyopathy.

摘要: Melas (mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes) is one of a group heterogeneous yet clinically distinct syndromes ascribed to defect in mitochondrial function. Here, the case patient diagnosed MELAS syndrome who subsequently developed acute renal failure reported. Although no clear insult was evident at time, clinical picture consistent diagnosis tubular necrosis. The patient9s function returned baseline. This article reviews literature concerning involvement encephalomyopathies, including MELAS, proposes mechanism by which patients suffering from disorders may be more susceptible hypoxic injury failure.