Angiotensin II directly increases transforming growth factor β1 and osteopontin and indirectly affects collagen mRNA expression in the human heart
作者： Claudio Kupfahl , Daniel Pink , Katharina Friedrich , Heinz R Zurbrügg , Michael Neuss
DOI: 10.1016/S0008-6363(00)00037-7
关键词: Stimulation 、 Pathogenesis 、 Fibroblast 、 Endocrinology 、 Angiotensin II 、 Transforming growth factor 、 Fibronectin 、 Internal medicine 、 Messenger RNA 、 Biology 、 Osteopontin
摘要: Objectives: Angiotensin II (Ang II) induces fibroblast proliferation and collagen synthesis in the myocardium, but its precise mechanisms of action in human hearts are still unknown. …
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