The schistosome in the mammalian host: understanding the mechanisms of adaptation.

摘要: In this review, we envisage the host environment, not as a hostile one, since schistosome thrives there, but one in which relationship between two organisms consists of constant communication, through signalling mechanisms involving sense organs, surface glycocalyx, membrane and internal organs parasite, with fluids cells. The secretions egg have very different properties from those other parasite stages, adapted for dispersal eggs preservation liver function. We draw studies mammalian cells to indicate how further work might be carried out on function raft structure existence pores membrane, repair role ion channel (including recent actin cytoskeleton calcium channels) possible P-glycoproteins adaptation its environment. are speculative some areas, such suggestions that variability schistosomes may relate rafts communities exhibit quorum sensing. This approach is adopted hope future whole their interactions will encouraged.