Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus

作者: Federico Cocozza , Nathalie Névo , Ester Piovesana , Xavier Lahaye , Julian Buchrieser

DOI: 10.1002/JEV2.12050

关键词: VirusTMPRSS2Cell biologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)InfectivityReceptorPriming (immunology)LentivirusLipid bilayer fusionChemistry

摘要: … In addition, although Caco-2 and Calu-3 expressed TMPRSS2, this protease was not released in EVs (Figure 1c). To obtain EVs with high amounts of ACE2 and TMPRSS2 to be tested …

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