Osteomyelitis and the role of biofilms in chronic infection.

作者: Rebecca A. Brady , Jeff G. Leid , Jason H. Calhoun , J. William Costerton , Mark E. Shirtliff

DOI: 10.1111/J.1574-695X.2007.00357.X

关键词: MicrobiologyStaphylococcus aureusImmunologyBiologyBacteriaMolecular interactionsOsteomyelitisBiofilmCoccusChronic infectionPhenotype

摘要: Understanding the mechanisms implicated in initial attachment, development, and maturation of a biofilm phenotype are tremendous importance for their effect on medical, industrial, public health arenas. This review explores current understanding nature biofilms impact that molecular interactions between bacteria themselves, as well host, may have development using nonmotile Gram-positive coccus, Staphylococcus aureus, an example.

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