Network of nuclear receptor ligands in multiple sclerosis: Common pathways and interactions of sex-steroids, corticosteroids and vitamin D3-derived molecules.

作者: Linda Rolf , Jan Damoiseaux , Raymond Hupperts , Inge Huitinga , Joost Smolders

DOI: 10.1016/J.AUTREV.2016.07.002

关键词: Function (biology)ImmunologyImmune systemCentral nervous systemVitamin D and neurologyMultiple sclerosisNuclear receptorMyeloidReceptorBiology

摘要: … Understanding of the intricate interactions between sex-steroids, corticosteroids and vitamin … in multiple sclerosis, the prototypic immune-driven disease of the central nervous system. …

参考文章(229)
J. W. Thornton, Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions Proceedings of the National Academy of Sciences of the United States of America. ,vol. 98, pp. 5671- 5676 ,(2001) , 10.1073/PNAS.091553298
Mark R. Mizee, Philip G. Nijland, Susanne M. A. van der Pol, Joost A. R. Drexhage, Bert van het Hof, Reina Mebius, Paul van der Valk, Jack van Horssen, Arie Reijerkerk, Helga E. de Vries, Astrocyte-derived retinoic acid: a novel regulator of blood–brain barrier function in multiple sclerosis Acta Neuropathologica. ,vol. 128, pp. 691- 703 ,(2014) , 10.1007/S00401-014-1335-6
Susan Kovats, Estrogen receptors regulate innate immune cells and signaling pathways. Cellular Immunology. ,vol. 294, pp. 63- 69 ,(2015) , 10.1016/J.CELLIMM.2015.01.018
S. O. Frederiksen, R. Ekman, C.-G. Gottfries, E. Widerlöv, S. Jonsson, Reduced concentrations of galanin, arginine vasopressin, neuropeptide Y and peptide YY in the temporal cortex but not in the hypothalamus of brains from schizophrenics Acta Psychiatrica Scandinavica. ,vol. 83, pp. 273- 277 ,(1991) , 10.1111/J.1600-0447.1991.TB05539.X
Isaias Glezer, Carolina Demarchi Munhoz, Elisa Mitiko Kawamoto, Tania Marcourakis, Maria Christina Werneck Avellar, Cristoforo Scavone, MK-801 and 7-Ni attenuate the activation of brain NF-κB induced by LPS Neuropharmacology. ,vol. 45, pp. 1120- 1129 ,(2003) , 10.1016/S0028-3908(03)00279-X
L.I. Garay, M.C. González Deniselle, M.E. Brocca, A. Lima, P. Roig, A.F. De Nicola, Progesterone down-regulates spinal cord inflammatory mediators and increases myelination in experimental autoimmune encephalomyelitis Neuroscience. ,vol. 226, pp. 40- 50 ,(2012) , 10.1016/J.NEUROSCIENCE.2012.09.032
A. Grasser, A. Möller, H. Backmund, A. Yassouridis, F. Holsboer, Heterogeneity of hypothalamic-pituitary-adrenal system response to a combined dexamethasone-CRH test in multiple sclerosis Experimental and Clinical Endocrinology & Diabetes. ,vol. 104, pp. 31- 37 ,(2009) , 10.1055/S-0029-1211419
Elena W. Bingaman, Debra J. Magnuson, Thackery S. Gray, Robert J. Handa, Androgen inhibits the increases in hypothalamic corticotropin-releasing hormone (CRH) and CRH-immunoreactivity following gonadectomy. Neuroendocrinology. ,vol. 59, pp. 228- 234 ,(1994) , 10.1159/000126663
R. B. Simerly, L. W. Swanson, C. Chang, M. Muramatsu, Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study. The Journal of Comparative Neurology. ,vol. 294, pp. 76- 95 ,(1990) , 10.1002/CNE.902940107
D D Bikle, E Gee, B Halloran, J G Haddad, Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease. Journal of Clinical Investigation. ,vol. 74, pp. 1966- 1971 ,(1984) , 10.1172/JCI111617