Cost‐Effectiveness of the 4 Pillars Practice Transformation Program to Improve Vaccination of Adults Aged 65 and Older

摘要: Objectives To estimate the cost-effectiveness of an intervention to increase pneumococcal, influenza, and pertussis-containing vaccine uptake in adults aged 65 older primary care practices. Design Markov decision analysis model, comparing 4 Pillars Practice Transformation Program with no intervention. Setting Diverse practices two U.S. cities. Participants Clinical trial participants older. Measurements Quality-adjusted life years (QALYs), public health outcomes, costs. Vaccination rates costs were derived from a randomized controlled cluster trial. Other parameters medical literature Centers for Disease Control Prevention data. All individually simultaneously varied over their distributions. Results With program extrapolating 10 years, there would be approximately 60,920 fewer influenza cases, 2,031 pertussis 13,842 pneumococcal illnesses older. Total per-person vaccination illness $23.93 higher than without intervention, concurrent effectiveness 0.0031 QALYs, or $7,635 per QALY gained. In sensitivity analyses, individual parameter variation caused cost more $50,000 gained. Conclusions Implementing based on is cost-effective undertaking individuals older, predicted benefits.