作者: Alfred A. Mina , Holly A. Bair , Greg A. Howells , Phillip J. Bendick
DOI: 10.1097/01.TA.0000063271.05829.15
关键词: Chemoprophylaxis 、 Prospective cohort study 、 Anticoagulant 、 Injury Severity Score 、 Anesthesia 、 Head injury 、 Head trauma 、 Surgery 、 Warfarin 、 Mortality rate 、 Medicine
摘要: Background: The frequency of use warfarin anticoagulation increases significantly in the elderly population. It remains controversial whether this puts these patients at increased risk for hemorrhagic complications after trauma. Methods: We prospectively evaluated consecutive trauma who were taking and compared their outcomes to a group age-matched with head injuries but not warfarin. Results: One hundred fifty-nine on evaluated, 94 (59%) some type trauma; 25 (27%) had documented intracranial Fifteen died (9.4%); they an international normalized ratio 3.3 ± 1.6 versus 3.0 2.1 survivors (p = 0.585). Twelve deaths (48%). Three without injury (5%) other causes related or hemorrhage mean 13 days admission. Ten 12 loss consciousness (LOC); two secondary isolated no LOC. Of 70 warfarin, 47 (67%) 5 (10%) < 0.001 both values study patients). There significant differences comparing those terms age, gender, mechanism injury, Injury Severity Score, Glasgow Come Scale score. Conclusion: conclude that preinjury does place patient fatal absence Furthermore, presence alone is predictive mortality. However, strongly associated mortality rate higher than are LOC also mortality, reliably indicate death.