Shuyu Capsules Relieve Premenstrual Syndrome Depression by Reducing and Expression in the Rat Brain
作者： Fang Li , Jizhen Feng , Dongmei Gao , Jieqiong Wang , Chunhong Song
DOI: 10.1155/2016/7950781
关键词: Capsule 、 Endocrinology 、 Depression (differential diagnoses) 、 Serotonin 、 Internal medicine 、 Hippocampal formation 、 Psychology 、 Mechanism of action 、 Shuyu 、 Receptor 、 Frontal lobe
摘要: The effects of the Shuyu capsule on 5-HT3AR and 5-HT3BR expression in a rat model premenstrual syndrome (PMS) depression hippocampal neuron 5-HT3 channel current were investigated, to elucidate its mechanism action against PMS depression. rats divided into Shuyu- fluoxetine-treated groups, which compared control for frontal lobe behavior. depressed displayed symptoms depression, reduced treated normal rats. Frontal levels significantly higher versus group lower group. As rats, 5-HT3R was higher; neurons with serum from than that those serum. Thus, may be related increased current. capsules rectified abnormal changes model; this finding provide insight treating
hindawi.com
core.ac.uk 参考文章(42)
Tian-Jin Li, Ovarian hormone modulates 5-hydroxytryptamine 3 receptors mRNA expression in rat colon with restraint stress-induced bowel dysfunction. World Journal of Gastroenterology. ,vol. 10, pp. 2723- 2726 ,(2004) , 10.3748/WJG.V10.I18.2723
Jianjian Peng, Chao Wang, Chao Wan, Dongdong Zhang, Wenjuan Li, Ping Li, Yan Kong, Liudi Yuan, miR-184 is Critical for the motility-related PNS development in Drosophila. International Journal of Developmental Neuroscience. ,vol. 46, pp. 100- 107 ,(2015) , 10.1016/J.IJDEVNEU.2015.07.006
Cai-Chun Liu, Yan-Fei Wu, Guang-Ming Feng, Xiao-Xia Gao, Yu-Zhi Zhou, Wen-Jing Hou, Xue-Mei Qin, Guan-Hua Du, Jun-Sheng Tian, Plasma-metabolite-biomarkers for the therapeutic response in depressed patients by the traditional Chinese medicine formula Xiaoyaosan: A 1H NMR-based metabolomics approach Journal of Affective Disorders. ,vol. 185, pp. 156- 163 ,(2015) , 10.1016/J.JAD.2015.05.005
A.B. El-Wishy, The postpartum buffalo. II. Acyclicity and anestrus Animal Reproduction Science. ,vol. 97, pp. 216- 236 ,(2007) , 10.1016/J.ANIREPROSCI.2006.03.003
Girstautė Dagytė, Ilaria Crescente, Folkert Postema, Laure Seguin, Cecilia Gabriel, Elisabeth Mocaër, Johan A. Den Boer, Jaap M. Koolhaas, Agomelatine reverses the decrease in hippocampal cell survival induced by chronic mild stress. Behavioural Brain Research. ,vol. 218, pp. 121- 128 ,(2011) , 10.1016/J.BBR.2010.11.045
Kun Lin, Yu-qi Liu, Bin Xu, Jin-liao Gao, Yi-cheng Fu, Yu Chen, Qiao Xue, Yang Li, Allocryptopine and benzyltetrahydropalmatine block hERG potassium channels expressed in HEK293 cells. Acta Pharmacologica Sinica. ,vol. 34, pp. 847- 858 ,(2013) , 10.1038/APS.2012.176
Chao Wang, Tongbao Feng, Qian Wan, Yan Kong, Liudi Yuan, miR-124 controls Drosophila behavior and is required for neural development. International Journal of Developmental Neuroscience. ,vol. 38, pp. 105- 112 ,(2014) , 10.1016/J.IJDEVNEU.2014.08.006
Lynda Uphouse, Female gonadal hormones, serotonin, and sexual receptivity. Brain Research Reviews. ,vol. 33, pp. 242- 257 ,(2000) , 10.1016/S0165-0173(00)00032-1
Tomasz Schneider, Piotr Popik, Increased depressive-like traits in an animal model of premenstrual irritability. Hormones and Behavior. ,vol. 51, pp. 142- 148 ,(2007) , 10.1016/J.YHBEH.2006.09.006
Mercedes Delgado, Anne G. Caicoya, Virginia Greciano, Bellinda Benhamú, María Luz López-Rodríguez, María Soledad Fernández-Alfonso, Miguel A. Pozo, Jorge Manzanares, José A. Fuentes, Anxiolytic-like effect of a serotonergic ligand with high affinity for 5-HT1A, 5-HT2A and 5-HT3 receptors. European Journal of Pharmacology. ,vol. 511, pp. 9- 19 ,(2005) , 10.1016/J.EJPHAR.2005.01.032