The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population‐Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight
作者： Sara Bandres‐Ciga , Sarah Ahmed , Marya S Sabir , Cornelis Blauwendraat , Astrid D Adarmes‐Gómez
DOI: 10.1002/MDS.27864
关键词: Political science 、 Population specific 、 Spanish population 、 Risk haplotype 、 Humanities 、 Christian ministry 、 Polygenic risk score
摘要: This research was supported, in part, by the Intramural Research Program of National Institutes Health (National Institute on Aging, Neurological Disorders and Stroke; project numbers: 1ZIA‐NS003154‐03, Z01‐AG000949‐02, Z01‐ES101986). In addition, this work supported Department Defense (award W81XWH‐09‐2‐0128), The Michael J Fox Foundation for Parkinson's Research, ISCIII Grants PI 15/0878 (Fondos Feder) to V.A. 15/01013 J,H. study grants from Spanish Ministry Economy Competitiveness (PI14/01823, PI16/01575, PI18/01898, [SAF2006‐10126 (2006‐2009), SAF2010‐22329‐C02‐01 (2010‐2012), SAF2013‐47939‐R (2013‐2018)]), co‐founded (Subdireccion General de Evaluacion y Fomento la Investigacion) Fondo Europeo Desarrollo Regional (FEDER), Consejeria Economia, Innovacion, Ciencia Empleo Junta Andalucia (CVI‐02526, CTS‐7685), Salud Bienestar Social (PI‐0437‐2012, PI‐0471‐2013), Sociedad Andaluza Neurologia, Jacques Gloria Gossweiler Foundation, Fundacion Alicia Koplowitz, Mutua Madrilena. Pilar Gomez‐Garre “Miguel Servet” (from ISCIII16 FEDER) “Nicolas Monardes” Andalusian Health) programmes. Silvia Jesus Maestre “Juan Rodes” programme, Daniel Macias‐Garcia “Rio Hortega” programme (both ISCIII‐FEDER). Cristina Tejera Parrado VPPI‐US Universidad Sevilla. has been conducted using samples HUVR‐IBiS Biobank (Andalusian Public System ISCIII‐Red Biobancos PT13/0010/0056). also grant PSI2014‐57643 CTS‐438 group a award Society Neurology.
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