Willingness to risk death endpoint in HIV cure-related research with otherwise healthy volunteers is misleading.

摘要: Abstract This viewpoint article critiques two recent articles examining ‘willingness to risk death’ advance HIV cure-related research. The endpoint sends the wrong signal research community about ongoing in otherwise healthy volunteers living with HIV. Socio-behavioural scientists have examined acceptability of a 99% death scenario, which is unrealistic and would not be acceptable by current regulatory ethical standards. We believe that field needs robust relevant socio-behavioural reflecting biomedical trials. These studies will need withstand scrutiny if cure or remission regimens are proceed licensing stage. must continue protect public trust sustain societal value generated such call for utmost prudence designing trials as well setting up experiments related these complex