Combinatorial antibody libraries and uses thereof
作者： Vaughn Smider , Helen Hongyuan Mao , Byeong Doo Song , James Graziano , Tyson Chase
DOI:
关键词: Biology 、 Antigen 、 Germline 、 Nucleic acid 、 Target protein 、 Molecular biology 、 Antibody 、 Computational biology
摘要: Methods for making a combinatorial antibody library from human germline segments are provided. Also provided libraries of nucleic acid molecules compiled encoding VL chains and VH chains, resulting libraries. The as addressable screening against target protein antigen, the identified or selected antibodies
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