作者: Stephan R. Thilen , Bradley E. Hansen , Ramesh Ramaiah , Christopher D. Kent , Miriam M. Treggiari
DOI: 10.1097/ALN.0B013E31826F8FDD
关键词: Anesthesia 、 Elective surgery 、 Neostigmine 、 Adductor pollicis muscle 、 Neuromuscular monitoring 、 Medicine 、 Prospective cohort study 、 Odds ratio 、 Paralysis 、 Surgery 、 Body mass index
摘要: BACKGROUND Residual paralysis is common after general anesthesia involving administration of neuromuscular blocking drugs (NMBDs). Management NMBDs and reversal frequently guided by train-of-four (TOF) monitoring. We hypothesized that monitoring eye muscles associated with more frequent residual than at the adductor pollicis. METHODS This prospective cohort study enrolled 180 patients scheduled for elective surgery anticipated use NMBDs. Collected variables included site, age, gender, weight, body mass index, American Society Anesthesiologists physical status class, type duration surgery, NMBDs, last total dose administered, TOF count time reversal, neostigmine, interval between to quantitative measurement. Upon postanesthesia care unit admission, we measured ratios acceleromyography was defined as a ratio less 90%. Multivariable logistic regression used account unbalances two groups adjust covariates. RESULTS 150 received were in analysis. Patients intraoperative had significantly greater incidence monitored pollicis (P < 0.01). observed 51/99 (52%) 11/51 (22%) patients, respectively. The crude odds 3.9 (95% CI: 1.8-8.4), adjusted 5.5 2.1-14.5). CONCLUSIONS having qualitative 5-fold higher risk postoperative those