High penetration drugs and their compositions thereof for treatment of parkinson diseases

摘要: One aspect of the invention provides a composition novel high penetration compositions (HPC) or prodrug (HPP) for treatment Parkinson's disease. The HPCs/HPPs are capable being converted to parent active drugs drug metabolites after crossing biological barrier and thus can render treatments conditions that can. Additionally, HPPs reaching areas may not be able access sufficient concentration at target therefore treatments. administered subject through various administration routes, e.g., locally delivered an action site condition with systematically enter general circulation faster rate.