Sustained release of bioactive protein from a lyophilized tissue-engineered construct promotes the osteogenic potential of mesenchymal stem cells.

作者: Moyuan Deng , Zhengqi Chang , Tianyong Hou , Shiwu Dong , Hao Pang

DOI: 10.1002/JOR.23027

关键词: Cell biologyGene expressionImmunologyStem cellLymphocyteDemineralized bone matrixProgrammed cell deathMesenchymal stem cellTissue engineeringCytokineChemistry

摘要: Tissue‐engineered constructs (TECs) seeded with mesenchymal stem cells (MSCs) represent a therapy for large bone defects. However, massive cell death in TECs in the early …

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