Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
作者： Robert D. Guzy , Beatrice Hoyos , Emmanuel Robin , Hong Chen , Liping Liu
DOI: 10.1016/J.CMET.2005.05.001
关键词: Cell biology 、 Oxygen 、 RNA interference 、 G alpha subunit 、 Reactive oxygen species 、 Biology 、 Coenzyme Q – cytochrome c reductase 、 Electron transport chain 、 Cytosol 、 Mitochondrion
摘要: … initiate adaptive responses when oxygen (O 2 ) … electron transport chain (ETC) is required for the hypoxic stabilization of HIF-1α and HIF-2α and that an increase in reactive oxygen …
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