High myopia and glaucoma susceptibility the Beijing Eye Study.

作者: Liang Xu , Yaxing Wang , Shuang Wang , Yun Wang , Jost B. Jonas

DOI: 10.1016/J.OPHTHA.2006.06.050

关键词: GlaucomaDioptrePopulationEmmetropiaOptic nerveOphthalmologyMedicineRefractive errorIntraocular pressureOptic disc

摘要: Objective To evaluate whether marked myopia, compared with moderate myopia and low is associated a higher prevalence of glaucomatous optic nerve damage. Design Population-based cross-sectional study. Participants Four thousand four hundred thirty-nine 5324 subjects 40 years or older were invited to participate (response rate, 83.4%). The group was stratified according refractive error into high (myopia > −8 diopters [D]), ( + 2 D) subgroups. Methods Morphologic assessment disc monoscopic photographs. Main Outcome Measures parameters intraocular pressure (IOP). Results For 4319 (97.3%) (8484 eyes), photographs evaluated. Prevalence atrophy as defined by the head appearance did not vary significantly P = 0.77; odds ratio [OR], 1.2; 95% confidence interval [CI], 0.38–3.81) between highly myopic myopia. In both groups combined, glaucoma frequency seemed be 0.075; OR, 2.28; CI, 0.99–5.25) than in myopia; it 0.001; 3.5; 1.71–7.25) 0.005; 4.23; 1.57–11.45) hyperopia. Glaucoma hyperopic emmetropic 0.17), 0.83), 0.32). Intraocular >0.10) any Similar results obtained for visual field defects. binary logistic regression analysis, presence Conclusions Marked exceeding −6 D may risk factor neuropathy.

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