Innate Immune Therapy For Cancer

摘要: Tumor cells usually express antigens which are distinguishable from normal “self” and thereby recognized by the host immune system. However, system barely responds to tumors in patients. Supplementation with adjuvant (such as BCG-CWS) patients cancer contributes regression of intrinsically growing cancer. The targets antigen-presenting cells, i.e. innate immunity, but not lymphocytes, promotes up-regulation MHC, co-stimulators initial cytokines cells. We hypothesized that role is provide conditions suitable for antigen-presentation where available lack adjuvant-induced priming results unresponsiveness tumor antigens. Here, we report therapy applicable supplementation adjuvants induction potent responses against tumors.